How the Liver Remembers: The Science Behind Intermittent Fasting
A new study reveals how repeated fasting enhances the liver’s ability to adapt through a cellular memory mechanism. The research shows that alternate-day fasting “sensitizes” key genes and liver enhancers, boosting ketogenesis during subsequent fasting bouts. This process, driven by the transcription factor PPARα, highlights how the body adjusts to recurring nutritional challenges. These findings provide fresh insights into the metabolic benefits of fasting and its potential applications in health and dietary science.